题目：Transcriptional Circuits, Cell Growth Dynamics and Shoot Meristem Development
地点：腾讯会议106 636 070
The research interest of Dr. Zhou’s group is to understand cellular and molecular mechanisms in control of shoot development and stem cell homeostasis, using both experimental and computational approaches. Our research centers on the stem-cell identity and function in the meristems of Arabidopsis and Ceratopteris, and we are interested in understanding: how stem cells are dynamically organized and maintained through continuous cell division, growth and differentiation; how developmental decisions are made during cell patterning and new organ formation; and how the regulatory circuits of transcription factors and microRNAs mediate cell fate specification and cell-cell communication. We are tackling these questions using multiple interdisciplinary methods, including confocal live cell imaging, computational quantification, modeling, biochemistry, molecular genetics, and functional genomics.
Jaiswal N, Liao C-J, Mengesha B, Han H, Lee S, Sharon A, Zhou Y, Mengiste T (2021) Regulation of plant immunity and growth by tomato receptor-like cytoplasmic kinase TRK1. New Phytologist. https://doi.org/10.1111/nph.17801.
Geng Y, Cai C, McAdam SAM, Banks JA, Wisecaver J, Zhou Y (2021) A De Novo Transcriptome Assembly of Ceratopteris richardii Provides Insights into the Evolutionary Dynamics of Complex Gene Families in Land Plants. Genome Biology and Evolution. https://doi.org/10.1093/gbe/evab042.
Wu X, Yan A, McAdam SAM, Banks, JA Zhang S, Zhou Y (2021) Timing of meristem initiation and maintenance determines the morphology of fern gametophytes. Journal of Experimental Botany. 72: 6990–7001. https://doi.org/10.1093/jxb/erab307.
Geng Y, Guo L, Han H, Liu X, Banks J, Wisecaver J, Zhou Y (2021) Conservation and diversification of HAIRY MERISTEM gene family in land plants. Plant Journal. https://doi.org/10.1111/tpj.15169.
Han H, Liu X, Zhou Y (2020) Transcriptional circuits in control of shoot stem cell homeostasis. Current Opinion in Plant Biology 53: 50-56.
Han H, Yan A, Li L, Zhu Y, Feng B, Liu X, Zhou Y (2020) A signal cascade originated from epidermis defines apical-basal patterning of Arabidopsis shoot apical meristems. Nature Communications. 11: 1214.
Han H, Geng Y, Guo L, Yan A, Meyerowitz EM, Liu X, and Zhou Y (2020). The Overlapping and Distinct Roles of HAM Family Genes in Arabidopsis Shoot Meristems. Frontiers in Plant Science. 11: 1375.
Zhu Y, Huang P, Guo P, Chong L, Yu G, Sun X, Hu T, Li Y, Hsu CC, Tang K, Zhou Y, Zhao C, Gao W, Tao WA, Mengiste T, Zhu JK (2020) CDK8 is associated with RAP2.6 and SnRK2.6 and positively modulates abscisic acid signaling and drought response in Arabidopsis. New Phytologist.228:1573-1590.
Geng Y, Zhou Y (2019) Confocal live imaging of shoot apical meristems from different plant species. J. Vis. Exp 145: e59369.
Zhou Y*, Yan A, Han H, Li T, Geng Y, Liu X, Meyerowitz EM* (2018) HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers. Science. 361: 502-506.